Diprolene is a artificial glucocorticoid that is used topically on the skin. Glucocorticoid have potent anti-inflammatory actions and also restrains the immune response. Diprolene is used for the aid of itching and inflammation associated with a wide variety of skin conditions.

Combination of potent glucocorticoids can increase the glucose concentration in the blood (this is especially worrisome in diabetics) and cause symptoms of glucocorticoid excess (weight gain, redistribution of fat stores, and psychiatric problems). The control of inflammation and the immune response caused by glucocorticoid excess also allows infections to occur more easily.

There are no known drug interactions with topical Diprolene. There is no data on the use of Diprolene in pregnant women. It is not known if Diprolene is secreted in breast milk.

The main commonly-noted side effects of Diprolene are burning at the part of application, itching, irritation, and dryness. All of these are unusual, however. Topical application of glucocorticoids may restrain the body’s production of cortisol. This is particularly true for potent products such as the augmented formulation of Diprolene. If suppression has happened for a long enough period of time, discontinuing the potent glucocorticoid can be associated with symptoms of glucocorticoid deficiency.

If Diprolene overdose is supposed, contact your local poison control center or emergency room immediately. A thin strip of betamethasone dipropionate cream or ointment is applied lightly to the affected area once or twice daily. A few drops of the lotion are applied to the affected area once or twice daily. The lotion should be massaged gently until it disappears. It should be kept between 20 and 30°C (36-86°F). Lotion should be shaken before each use.

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